RSC Advances

Palladium-catalyzed annulation reactions of methyl o-halobenzoates with azabicyclic alkenes: a general protocol for the construction of benzo [c] phenanthridine …

C Guo, K Huang, B Wang, L Xie, X Xu

Index: Guo, Cui; Huang, Kanglun; Wang, Bo; Xie, Longguang; Xu, Xiaohua RSC Advances, 2013 , vol. 3, # 38 p. 17271 - 17280

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Abstract

The annulation reaction of methyl o-halobenzoates with azabicyclic alkenes proceeds efficiently to give the corresponding benzo [c] phenanthridine derivatives in good to excellent yields using a developed base-free methodology based on our preliminary studies. Thirty-seven application examples validate the compatibility of the present strategy with different groups, particularly with the electron-deficient ones, that are difficult to ...