Design, synthesis and biological evaluation of pazopanib derivatives as antitumor agents

Y Jia, J Zhang, J Feng, F Xu, H Pan…

Index: Chemical Biology and Drug Design, , vol. 83, # 3 p. 306 - 316

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Citation Number: 9

Abstract

... Chemical Biology & Drug Design, 83: 306–316. ... The preliminary biological activity of all the target compounds against VEGFR-2, EGFR, AKT1, ALK1 and ABL1 were evaluated, and the anti-angiogenesis activities ex vivo of some compounds were also investigated. ... Chemistry. ...