Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co …

RJ Young, W Alderton, ADR Angell, PJ Beswick…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 10 p. 3037 - 3040

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Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... 27 It might be that subtle differences in redox chemistry across the isoforms, which give rise to selectivity in substrate based analogues, 28 contribute to this. ...