Canadian Journal of Chemistry

Synthesis of dl-threo-and dl-erythro-β-hydroxyisoleucine

TA Dobson, LC Vining

Index: Dobson,T.A.; Vining,L.C. Canadian Journal of Chemistry, 1968 , vol. 46, p. 3007 - 3012

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Citation Number: 11

Abstract

dl-threo-and dl-erythro-β-Hydroxyisoleucine were prepared from cis-and trans-3-methylpent- 2-enoic acids, respectively. The configuration of the erythro isomer was established from its synthesis by two independent routes. The diastereoisomers, and those of other β-hydroxy amino acids, can be distinguished by examination of their proton magnetic resonance spectra.