Pergamon Bioorganic & Medicinal Chemistry Letters, Vol. ... Chemistry, The substituted 4-benzylamino-2-methylpyrroio[2,3-d]pyrimidines 1 were prepared by displacement of the chloro group of 4-chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine 2 (3) in refluxing water with the ...