Synthesis and insecticidal activities of novel 1, 3, 4-thiadiazole 5-fluorouracil acetamides derivatives: An RNA interference insecticide

R Wan, JQ Zhang, F Han, P Wang, P Yu…

Index: Wan, Rong; Zhang, Jian-Qiang; Han, Fen; Wang, Peng; Yu, Peng; He, Qiu Nucleosides, Nucleotides and Nucleic Acids, 2011 , vol. 30, # 4 p. 280 - 292

Full Text: HTML

Citation Number: 14

Abstract

A series of novel 1, 3, 4-thiadiazole 5-fluorouracil acetamides derivatives were designed and synthesized. Their structures were confirmed by infrared, 1H NMR spectroscopy, and elemental analysis. The insecticidal activities against Tetranychus cinnabarinus and Aphis craccivora of these new compounds were evaluated. The bioassay tests showed that most of these title compounds possessed a good combination of stomach toxicity as well as ...