Abstract A novel series of N-arylpyrazole derivatives (5a–5d, 7a–7c) has been designed and synthesized via aromatic substitution reaction of N-nonsubstituted pyrazoles with 4- fluoronitrobenzene in the presence of base. The structures of these compounds were established on the basis of elemental (C, H, and N) and spectral analysis (1 H NMR, 13 C NMR, HRMS, and FT-IR). All the compounds were tested for their cytotoxic activity in vitro ...
