On the Synthesis of S-(X-Methyl) ribofura. osyl-l, 2, 3-triazole Nucleosides') The synthesis of the reactive 5-(bromomethyl)-l-(2', 3', 5'-tri-O-benzoyl-~-~-ribofuranosyl)-l, 2, 3-triazole (3) via 1 Jdipolar cycloaddition of the P-oxoalkylidenephosphorane 2 to the ribofuranosyl azide 1 under elimination of triphenylphosphane oxide is described. The nucleosides 4a-d are obtained by substitution of the bromide in 3 by N3-, SCN-, A d-and AcS-. With P (OCH3), 3 ...
