Palladium-and platinum-catalyzed addition of aldehydes and imines with allylstannanes. chemoselective allylation of imines in the presence of aldehydes

H Nakamura, H Iwama…

Index: Nakamura, Hiroyuki; Iwama, Hideki; Yamamoto, Yoshinori Journal of the American Chemical Society, 1996 , vol. 118, # 28 p. 6641 - 6647

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Citation Number: 235

Abstract

The reaction of allylstannanes 1 with aldehydes 2 in THF was catalyzed by Pd (II) or Pt (II) complexes (10 mol%) either at room temperature or at reflux, giving the corresponding homoallylic alcohols 3 in high to good yields. Among the catalysts examined, PtCl2 (PPh3) 2 gave the best result. No only allyltribitylstannane but also methallyl-and crotyltributylstannane could be utilized in this transition metal catalyzed reaction. Detailed ...