Abstract On heating, 5-nitropyrimidin-4-yl dialkyldithiocarbamates undergo two types of transformations. One type of these transformations involves intramolecular ipso-substitution of the nitro group to form bis (4-dialkylcarbamoylthiopyrimidin-5-yl) disulfides, whereas another type of transformations involves elimination of carbon disulfide to give 4, 6-diamino- 5-nitropyrimidine derivatives. The reaction pathway is controlled by the steric effect of the ...
