Catalytic Friedel–Crafts/Lactonization Domino Reaction: Facile Access to 3??Hydroxybenzofuran??2??one Scaffold

F Vetica, A Pelosi, A Gambacorta…

Index: Citterio; Gandolfi; Piccolo; et al. Synthesis, 1984 , vol. NO. 9, p. 760 - 763

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Abstract

... During the 1980s, Casiraghi11 and Citterio12 independently envisaged the possibility of obtaining benzofuran-2-one ... of few 3-hydroxy-3-(trifluoromethyl)benzofuran-2-ones [Equation (I), Scheme 1].13 More recently, Masciadri et al. ... 2, BF 3 ·Et 2 O, 30, CH 2 Cl 2, rt, 24, 36, trace. ...