A new series of thiophene- and furan-containing chromophores with a chiral prolinol donor and a sulfone acceptor has been synthesized. The UV-vis absorptions, second-order nonlinear optical properties, and X-ray crystal structures are described. ... Keywords: Nonlinear optical materials; Chiral; Heterocyclic compounds. ... The potential applications of nonlinear optical (NLO) materials in telecommunications, data storage, and optical in- formation processing ...