The work of Seide3 and of Mangini and Colonna4 has shown that two modes of cyclization exist for N-2-pyridyl benzoylacetamides. The amide derived from 2-aminopyridine gave 4- phenyl-2H-pyrido [l, 2-a] pyrimidine-2-one3 while that derived from 2; 6-diaminopyridine gave 2-hydroxy-4-phenyl-7-amino-1, 8-naphthyridine. 4 Similar results have been observed in other such cyclization reactions; for example, it has been shown6 that the reaction of ...
