Green Chemistry

Efficient and practical transition metal-free catalytic hydration of organonitriles to amides

T Tu, Z Wang, Z Liu, X Feng, Q Wang

Index: Tu, Tao; Wang, Zhixun; Liu, Zelong; Feng, Xike; Wang, Qingyi Green Chemistry, 2012 , vol. 14, # 4 p. 921 - 924

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Citation Number: 35

Abstract

As versatile synthons in organic synthesis and essential intermediates in pharmaceutical and material sciences, 1,2 amides played significant roles and exhibited a wide range of applications in academia and industry. 3 In contrast with other methodologies, hydration of organonitriles constitutes a more atom-economical and straightforward protocol to access various amides, which has been applied as an important technology in industry to produce a wide number of ...