Structure-activity relationships of trichothecene toxins in an Arabidopsis thaliana leaf assay

AE Desjardins, SP McCormick…

Index: Desjardins, Anne E.; McCormick, Susan P.; Appell, Michael Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6487 - 6492

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Citation Number: 49

Abstract

Many Fusarium species produce trichothecenes, sesquiterpene epoxides that differ in patterns of oxygenation and esterification at carbon positions C-3, C-4, C-7, C-8, and C-15. For the first comprehensive and quantitative comparison of the effects of oxygenation and esterification on trichothecene phytotoxicity, we tested 24 precursors, intermediates, and end products of the trichothecene biosynthetic pathway in an Arabidopsis thaliana detached ...