Journal of the Chilean Chemical Society

Synthesis and biological evaluation of some substituted amino thiazole derivatives

AK Prajapati, VP Modi

Index: Prajapati; Modi, Vishal P. Journal of the Chilean Chemical Society, 2010 , vol. 55, # 2 p. 240 - 243

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Citation Number: 11

Abstract

ABSTRACT Condensation of acetophenone with thiourea in presence of halogen (Iodine) gives 2-amino-4-phenylthiazole (I). 2-Amino-4-phenyl-5-phenylazothizole (II) was prepared by coupling of phenyldiazonium chloride with 2-amino-4-phenylthiazole (I). A series of amide can be synthesized by treatment of appropriate substituted acid chlorides (III) with compound (II) using pyridine as solvent. All the synthesized compounds are characterized ...