Thiocarbohydrazide and substituted benzoyl hydrazine were used as starting materials to synthesize fifteen fluorinated 3, 5-disubstituted-4H-1, 2, 4-triazol-4-amines. All the title compounds were characterized using IR, 1H and 19F NMR spectroscopy, mass spectrometry (MS) and elemental analysis. The structures of compounds 6g and 7 were confirmed by X-ray diffraction crystallography. The preliminary bioassay results showed ...
