Structure-activity studies of 6-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 2. Effects of distal acid bioisosteric substitution, …

PL Ornstein, MB Arnold, NK Allen…

Index: Journal of Medicinal Chemistry, , vol. 39, # 11 p. 2232 - 2244

Full Text: HTML

Citation Number: 43

Abstract

... Journal of Medicinal Chemistry. ... Our medicinal chemistry research efforts are targeted toward the identification of compounds which are potent and selective antagonists of excitatory amino acid (EAA) receptors, 1 with the goal of developing these compounds as novel ... Chemistry. ...