The Journal of Organic Chemistry

Synthesis of α-Amino-γ-hydroxy Acids: γ, γ'-Dihydroxyvaline

E Galantay, A Szabo, J Fried

Index: Galantay,E. et al. Journal of Organic Chemistry, 1963 , vol. 28, p. 98 - 102

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Citation Number: 21

Abstract

Until a few years ago, homoserine was the only a-amino-y-hydroxy acid known with certainty to occur in Nature. Recently, however, a prodigious number of such compounds has been detected, both in free form and as peptide constituents and their chemistry has been the subject of considerable study.'We wish to describe a simple synthetic method leading to a- amino acids with chain branching in the beta position and carrying hydroxyl groups in one ...