Liebigs Annalen der Chemie

A new approach to allylamines and pyrrolidines

T Gajda, A Zwierzak

Index: Gajda, Tadeusz; Zwierzak, Andrzej Liebigs Annalen der Chemie, 1986 , # 6 p. 992 - 1002

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Citation Number: 2

Abstract

Abstract The 1, 4-adducts 3a–c and 4, readily available from the reaction between diethyl N, N-dichlorophosphoramidate (1) and 1, 3-dienes, were found to be convenient precursors for the efficient synthesis of the δ-chloroallylamine hydrochlorides 5a–d and N-phosphorylated allylamines 6a–c and 7. The three-step transformation of 3a–c affords the cis-3, 4- dibromopyrrolidine hydrochlorides 10a–c. The preparation of the 2, 5-dihydro-1H-pyrrole ...