A NEW AND CONVENIENT PREPARATION OF 3-BROMO-4-CHLORONITROBENZENE

K Kosandal, AKS Bhujanga Rao, CG Rao…

Index: Kosandal, Kantilal; Rao, A. K. S. Bhujanga; Rao, C. Gundu; Singh, B. B. Organic Preparations and Procedures International, 1991 , vol. 23, # 3 p. 395 - 396

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Citation Number: 3

Abstract

In the course of our studies on the synthesis of the potent antibacterials “fluoroquinolones”,'3- bromo-4-chloronitrobenzene was needed on a large scale. A low yield multi-step synthesis involving exhaustive purification has been described? Although several mild methods are available for bringing about electrophilic bromination of activated aromatic compounds, very few have been reported for deactivated rings. We now describe a simple one-step ...