Useful synthetic method of polypeptides with well??defined structure by polymerization of activated urethane derivatives of α??amino acids

S Yamada, K Koga, T Endo

Index: Koga, Koichi; Sudo, Atsushi; Endo, Takeshi Journal of Polymer Science, Part A: Polymer Chemistry, 2010 , vol. 48, # 19 p. 4351 - 4355

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Citation Number: 21

Abstract

INTRODUCTION Polypeptides have received great attention as promising components for new design of various macromolecular architectures, 1–5 because of its intriguing feature such as a-helix and b-sheet. For polypeptide synthesis, various synthetic strategies have been developed. Small peptide sequences were generally synthesized by stepwise solid- phase synthesis, whereas, for synthesis of high molecular weight polypeptides, living ring- ...