Synthesis of 1-fluoro-, 4-fluoro-, and 1, 4-difluoro-4-demethoxydaunomycinone. Interesting D-ring analogs of adriamycin

GW Morrow, JS Swenton, JA Filppi…

Index: Journal of Organic Chemistry, , vol. 52, # 5 p. 713 - 719

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Citation Number: 28

Abstract

THE JOURNAL OF Organic Chemistry ... Synthetic routes to anthracyclinones have been of major interest in organic chemistry for the last decade.l A major objective of this work has been the development of viable syntheses of anthracyclinone aglycons that upon ... 714 J. Org. ...