Synthetic approach toward the partial sequences of betaglycan in the linkage region on solid support and in solution phase

…, A Yamaguchi, J Tanaka, Y Nishimura

Index: Tamura, Jun-Ichi; Yamaguchi, Akihiro; Tanaka, Junko; Nishimura, Yuko Journal of Carbohydrate Chemistry, 2007 , vol. 26, # 2 p. 61 - 82

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Citation Number: 5

Abstract

We have synthesized, for the first time, the partial sequence of the betaglycan composed of the tetraosyl hexapeptide, which was directly usable as a probe for enzymatic glycosyl transfer. Stepwise elongation afforded the corresponding tetraosyl trichloroacetimidate. The common glycosyl dipeptide:[β??d??GlcA??(1→ 3)?螃漫?d??Gal??(1→ 3)?螃漫?d??Gal??(1→ 4)?螃漫?d??Xyl?? (1→ O)??Ser??Gly] was synthesized by glycosylation of the corresponding tetraosyl ...