Synthesis and quantitative structure-activity relationships of anticonvulsant 2, 3, 6-triaminopyridines

JK Seydel, KJ Schaper, EA Coats…

Index: Journal of Medicinal Chemistry, , vol. 37, # 19 p. 3016 - 3022

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Citation Number: 29

Abstract

... Journal of Medicinal Chemistry, 1994, Vol. 37, No. ... Structure - Ac tivi ty Rela tionships The in vivo pharmacological test data on neurotoxicity and anticonvulsant activity were subjected to multipa- rameter regression analysis in an effort to elucidate chemical features affecting ...