Atriopeptins. I. Synthesis of C-terminal fragments

MV Ovchinnikov, ZD Bespalova…

Index: Ovchinnikov, Mikhail V.; Bespalova, Zhanna D.; Molokoedov, Aleksandr S.; Revenko, Inna V.; Sepetov, Nikolai F.; et al Collection of Czechoslovak Chemical Communications, 1989 , vol. 54, # 3 p. 772 - 783

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Citation Number: 2

Abstract

In 1981 it has been shownl that application of rat atrial extracts increased excretion of sodium ions and water in experimental animals. The discovery that the atrium contains a factor exhibiting strong natriuretic effect has given impetus to many investigations resulting in the isolation of several so-called atriopeptins and deter- mination of their structure. Several recent reviews and papers2 - 5 discuss the physio- logical function of these compounds. It is assumed that ...