Investigation of functionally liver selective glucokinase activators for the treatment of type 2 diabetes

GR Bebernitz, V Beaulieu, BA Dale…

Index: Journal of Medicinal Chemistry, , vol. 52, # 19 p. 6142 - 6152

Full Text: HTML

Citation Number: 69

Abstract

... Journal of Medicinal Chemistry. ... 10−15 years. Glucokinase (GK) activators are currently under investigation by a number of pharmaceutical companies with only a few reaching early clinical evaluation. A GK activator ...