Reformatsky reaction with halolactones. I. Reaction with nonsteroid carbonyl compounds

H Torabi, RL Evans, HE Stavely

Index: Torabi,H. et al. Journal of Organic Chemistry, 1969 , vol. 34, # 12 p. 3792 - 3796

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Citation Number: 5

Abstract

The classical Reformatsky reaction proceeds normally when a-bromolactones replace a- bromo esters. A variety of aromatic carbonyl compounds and one alicyclic ketone were condensed with a-bromo-ybutyrolactone to yield both hydroxy and unsaturated addition products. 4, 4'-Dimethoxybenzophenone and a-bromo-r-butyrolactone reacted normally in benzene-ether solvents, but, when tetrahydrofuran was used as a solvent, a major product ...