Chemistry Letters

Oxidative removal of heterocyclic alkyl or sugar side chain by microwave: A simple step to xanthopterin, 6-formylpterin, and 3-hydroxymethyl-2 (1H)-quinoxalinone

S Goswami, AC Maity

Index: Goswami, Shyamaprosad; Maity, Annada C. Chemistry Letters, 2007 , vol. 36, # 9 p. 1118 - 1119

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Citation Number: 11

Abstract

One-step microwave-assisted oxidative removal of 3-methyl and 3-sugar side chain in 2 (1H)-quinoxalinone system by selenium dioxide and sodium periodate respectively resulting 2 (1H)-quinoxalinone has been reported. Similarly xanthopterin (as acetyl derivative 11) was isolated from selenium dioxide oxidation of 7-methylxanthopterin. In the absence of adjacent lactam moiety, sodium periodate efficiently oxidizes 2-acetylaminopterin tetrols 7 and 8 to ...