to the crude Swern oxidation of 1, 2-octanediol quenched the bright yellow color characteristic of hexylglyoxal1 instantaneously at-78 OC, and the Wittig condensation product 911 was isolated in 90% yield. This constitutes a simple new method for the synthesis12 of the y-oxygenated crotonates found in several natural products. 13 As an even more demanding test of this protocol, we selected the hitherto unknown parent acylsilane,( ...
