Synthesis and biological activity of 2-hydroxyalkylammonium salts of [organothio] acetic acids

GG Levkovskaya, YI Kryukova, ÉÉ Kuznetsova…

Index: Levkovskaya, G. G.; Kryukova, Yu. I.; Kuznetsova, E. E.; Dolgushina, G. S.; Pushechkina, T. A.; et al. Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 6 p. 404 - 407 Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 6 p. 679 - 683

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Abstract

Aroxyalkanecarboxylic acids of the type ArOC (RtR2) COOR and their derivatives are used in agriculture as herbicides and plant-growth stimulators [I], and in medicine as hypocholesterolemic, hypolipidemic, and antiarrhythmic agents [2, 3]; they also exhibit antitumor activity [4]. The biological properties of their sulfur analogs--the (organothio) alkanecarboxylic acids and their derivatives, which contain four and six-valent sulfur-- ...