Summary. Diethyl 3, 3′-di-tert-butyl-4, 4′-dimethyl-2, 2′-bipyrrole-5, 5′-dicarboxylate was synthesized in four steps from ethyl 3, 5-dimethyl-1 H-pyrrole-2-carboxylate. The CH 2 hydrogens of the ethyl ester groups of the former are diastereotopic in the 1 H-NMR, consistent with axial chirality of the bipyrrole and restricted rotation about the 2, 2′-bipyrrole bond, due to the tert-butyl groups. An X-ray structure of the crystalline target compound ...
