A new ring opening reaction of N??aminophthalimide hydrazones

…, J Rosenberg, ML Campbell

Index: Hearn, Michael J.; Rosenberg, Judith; Campbell, Mary L. Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1405 - 1407

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Abstract

Abstract Araldehyde hydrazones III of N-aminophthalimide underwent rapid ring opening reactions initiated by the addition of excess base to their refluxing methanolic solutions. The products were conveniently isolated through liquid-liquid extraction as the stable sodium salts V, and acidification precipitated the resulting phthalic acid congeners VI from aqueous solution. Compounds III readily exchanged one hydrazine moiety for another. For example ...