Reactions of 2, 3??dihydrospiro [1H??4??and 5??azabenzimidazole??2, 1′??cyclohexane] with nucleophiles: A potential route to some substituted aromatic heterocycles

…, W Kramer, R Neidlein, H Suschitzky

Index: Reizner, Ralf; Kramer, Walter; Neidlein, Richard; Suschitzky, Hans Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 1 p. 117 - 128

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Abstract

Abstract The readily available title compounds 2, 16 and 27 react with pseudohalogenes (cyanide, azide), carbon and heterocyclic N-nucleophiles in the presence of manganese dioxide to give the corresponding substituted azaisobenzimidazoles (= 2H- azabenzimidazoles) 4, 8, 23–26 and 29–33, 36 or dihydroazabenzimidazoles (= 2, 3- dihydro-1H-azabenzimidazoles 7, 22, 34 and 35. In 8 one of the two imidazolyl- ...