Abstract Malaria is a potentially fatal disease caused by Plasmodium parasites and poses a major medical risk in large parts of the world. The development of new, affordable antimalarial drugs is of vital importance as there are increasing reports of resistance to the currently available therapeutics. In addition, most of the current drugs used for chemoprophylaxis merely act on parasites already replicating in the blood. At this point, a ...
[Appel, Eric A.; Biedermann, Frank; Rauwald, Urs; Jones, Samuel T.; Zayed, Jameel M.; Scherman, Oren A. Journal of the American Chemical Society, 2010 , vol. 132, # 40 p. 14251 - 14260]