It is known that the steric requirements for the interactions of catecholamines and catecholimidazolines with al-and a2-adrenoceptors are different. New analogues of desoxycatecholimidazoline (l), desoxycatecholimidazole (3), benzylic hydroxyl substituted imidazole (4), and the aromatic fluorine substitution analogues of 1 at the 2 (5), 5 (6), and 6 (7) positions, and a set of asymmetric 4-substituted catecholimidazolines, S-8 and R-8, ...
