Synthetic Communications

Synthesis of (L)-4-Fluorotryptophan

DW Konas, D Seci, S Tamimi

Index: Konas, David W.; Seci, Drilona; Tamimi, Safa Synthetic Communications, 2012 , vol. 42, # 1 p. 144 - 152

Full Text: HTML

Citation Number: 1

Abstract

Fluorinated amino acids are important tools for biological and medicinal chemists. Substitution of fluorine for hydrogen within the natural amino acid structure often results in a product with significantly altered physical and chemical properties, which is still recognized and accepted in biological systems. As a result, fluoroamino acids and larger compounds containing them have been widely used as biochemical probes, alternate enzyme substrates, and enzyme ...