The Journal of Organic Chemistry

Synthesis and configurational assignment of geiparvarin: a novel antitumor agent

PJ Jerris, AB Smith III

Index: Jerris, Paula J.; Smith, Amos B. Journal of Organic Chemistry, 1981 , vol. 46, # 3 p. 577 - 585

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Citation Number: 83

Abstract

This report presents the fit total synthesis of geiparvarin as well as wignment of configuration of the previously undefined trisubstituted olefin. A central aspect of this synthetic adventure leading to this novel antitumor agent which possesses the 3 (2H)-furanone ring system ...