The Journal of organic chemistry

Synthesis of benzo [b] furans via CuI-catalyzed ring closure

C Chen, PG Dormer

Index: Chen, Cheng-Yi; Dormer, Peter G. Journal of Organic Chemistry, 2005 , vol. 70, # 17 p. 6964 - 6967

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Citation Number: 103

Abstract

Benzo[b]furans are of great synthetic interest because of their wide distribution in nature and useful biological activities. 1 The benzo[b]furan ring is often incorporated in pharmaceutical agents as a core structural motif, and as a result continues to attract extensive synthetic efforts. 2,3 Many reported synthetic approaches are based on the construction of furan rings from various arene derivatives via different bond formation. 3h In contrast, very few examples of ...