Synthesis of novel thioglycoside derivatives containing quinazolinone

H Huang, JF Gao, LH Cao, DZ Wang…

Index: Huang, Hui; Gao, Jian-Fang; Cao, Ling-Hua; Wang, Duo-Zhi; Zhang, Jian-Bin; Zhou, Shu-Bao; Zhou, Yu-Qiang Journal of the Chinese Chemical Society, 2009 , vol. 56, # 2 p. 419 - 424

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Citation Number: 3

Abstract

Abstract A series of novel thioglycoside derivatives containing 4 (3H)-quinazolinone was designed and synthesized from 2-chloromethyl-quinazolin-4 (3H)-ones and 1-thioglycose. Several 2-chloromethyl-quinazolin-4 (3H)-ones were synthesized on refluxing with 2- (chloroacetylamino)-benzoic acid and arylamines in acetonitrile. All of the novel compounds were characterized by IR, 1 H NMR spectra and elemental analysis. The structures of ...