Alkynylpyrimidine amide derivatives as potent, selective, and orally active inhibitors of Tie-2 kinase

VJ Cee, BK Albrecht, S Geuns-Meyer…

Index: Journal of Medicinal Chemistry, , vol. 50, # 4 p. 627 - 640

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Citation Number: 36

Abstract

... Journal of Medicinal ... Departments of Medicinal Chemistry, Molecular Pharmacology, and Molecular Structure, Amgen Inc., One Kendall Square, Bldg. ... pp 627–640. DOI: 10.1021/jm061112p. Publication Date (Web): January 25, 2007. Copyright © 2007 American Chemical Society ...