Chemical and pharmaceutical bulletin

Formation of cyanide ion or cyanogen chloride through the cleavage of aromatic rings by nitrous acid or chlorine. X. Pathway of cyanogen chloride formation in the …

T OHYA, S KANNO

Index: Ohya, Takeshi; Kanno, Saburo Chemical and Pharmaceutical Bulletin, 1988 ,  vol. 36,  # 10  p. 4095 - 4102

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Citation Number: 4

Abstract

The pathway in the formation of cyanogen chloride from the reaction of 1-naphthol (1) and 4- phenylimidazole with chloramine was investigated. The intermediates isolated in the reaction of 1-naphthol (1) with chloramine were N-chloro-1, 2-naphthoquinone 2-imine (2) and o-carboxycinnamonitrile (6), the latter of which, liberating cyanogen chloride, was finally converted tophthalide-3-carboxylic acid (8). The products obtained in the reaction of 4- ...