A simple four-step synthetic method for 7-iodo-, 7-bromo- and 7-chloroindole was established with high overall yield starting from 2,3-dihydroindole. Several 7-substituted indoles carrying a carbon side chain and 7-methoxyindole were also synthesized. Keywords thallation; 7-substituted indole; regioselective metalation; 7-iodoindole; 7- bromoindole; 7-chloroindole; 7-methoxyindole; methyl 3-(indol-7-yl)acrylate; 4-(indo1-7-y1)- 2-methy1-3-buten-2-ol; ...
