Practical and stereocontrolled approaches to polyfluorinated synthetic pyrethroids based on aldehyde addition of CF 3 CCl 2 ZnCl are described. The zinc reagent was allowed to react with 3-formyl-2, 2-dimethylcyclopropanecarboxylates (6) to give the corresponding adducts. These were acetylated and then reduced again with zinc to afford (1R*, 3S*)-3-(2-chloro-3, 3, 3-trifluoro-1-propenyl)-2, 2-dimethylcyclopropanecarboxylates (12). The (1R*, 3R*)- ...
![(2-methyl[1,1'-biphenyl]-3-yl)methyl cis,trans-2,2-dimethyl-3-formylcyclopropanecarboxylate Structure](https://image.chemsrc.com/caspic/077/107489-30-5.png)
