Design, synthesis, and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic …

E Teodori, E Baldi, S Dei, F Gualtieri…

Index: Bellucci; Teodori; Gualtieri Farmaco, Edizione Scientifica, 1985 ,  vol. 40,  # 10  p. 730 - 744

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Citation Number: 38

Abstract

Several compounds with a 4-aminopiperidine scaffold decorated on both nitrogen atoms by alkyl or acyl moieties containing the structural motifs of verapamil and of flunarizine, as well as those that are more frequent in known N-type calcium channel antagonists, have been