Bioorganic & medicinal chemistry

Synthesis of 3-substituted benzamides and 5-substituted isoquinolin-1 (2H)-ones and preliminary evaluation as inhibitors of poly (ADP-ribose) polymerase (PARP)

CY Watson, WJD Whish, MD Threadgill

Index: Bioorganic and Medicinal Chemistry, , vol. 6, # 6 p. 721 - 734

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Citation Number: 73

Abstract

... JavaScript is disabled on your browser. Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry. Volume 6, Issue 6, June 1998, Pages 721–734. Cover image Cover image. ... 1.2. Chemical synthesis: Isoquinolin-1-ones. ...

5-Benzamidoisoquinolin-1-ones and 5-(ω-carboxyalkyl) isoquin...

[Sunderland, Peter T.; Woon, Esther C. Y.; Dhami, Archana; Bergin, Aoife B.; Mahon, Mary F.; Wood, Pauline J.; Jones, Louise A.; Tully, Sophie R.; Lloyd, Matthew D.; Thompson, Andrew S.; Javaid, Hashim; Martin, Niall M. B.; Threadgill, Michael D. Journal of Medicinal Chemistry, 2011 , vol. 54, # 7 p. 2049 - 2059]