Abstract As an extension of previous studies on the total synthesis of (2R, 4′ R, 8′ R)-α- tocopherol (1)[1][2],(S)-(−)-2-(6-benzyloxy-2, 5, 7, 8-tetramethylchroman) acetic acid (6), a pivotal intermediate, possessing the absolute configuration required for construction of 1 was prepared by optical resolution of the racemic modification 11. the latter substance was obtained by two routes, one emanating from the hydroxy acetal 7 [1] and the other based ...
