Abstract Nonadrenergic imidazoline binding sites (imidazoline I2 sites) have been described to be colocated with monoamine oxidase (MAO) in the mitochondrial fraction of various cell types. In the present work, the authors considered whether this colocation could be associated with a functional interplay. In rat liver membranes,[3H]-idazoxan binding to I2 receptors was competed for by naphazoline and idazoxan, which also shared a high ...
