e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Journal of organometallic chemistry
Zirconocene-catalyzed alkylative dimerization of 2-methylene-1, 3-dithiane via a single electron transfer process to provide symmetrical vic-bis (dithiane) s
A mixture of tertiary alkyl halide and 2-methylene-1, 3-dithiane was treated with butylmagnesium bromide in the presence of a catalytic amount of zirconocene dichloride. The reaction resulted in alkylative dimerization to yield the corresponding vic-bis (dithiane). The reaction would proceed as follows. A single electron transfer from low-valent zirconocene to alkyl halide would generate the corresponding alkyl radical. The radical ...