Protection of primary amines as N-substited 2, 5-dimethylpyrroles

SP Breukelman, GD Meakins, MD Tirel

Index: Breukelman, Stephen P.; Meakins, G. Denis; Tirel, Malcolm D. Journal of the Chemical Society, Chemical Communications, 1982 , # 14 p. 800 - 801

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Citation Number: 10

Abstract

Protection of a primary amine group against attack by organic or aqueous solutions of strong bases or nucleophiles is achieved by incoporation into an N-substituted 2, 5-dimethylpyrrole system from which the amine group is regenerated by treatment with hydroxylamine hydrochloride.